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Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemicpost-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 301-305 doi: 10.1007/s11684-013-0283-1

Abstract: Ischemic post-conditioning (IPostC) has emerged as a promising method for myocardial protection against

Keywords： adiponectin     ischemic post-conditioning     ischemia reperfusion injury     diabetes    

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Interactions between remote ischemic conditioning and post-stroke sleep regulation

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 867-876 doi: 10.1007/s11684-021-0887-9

Abstract: As a multi-targeted nonpharmacological intervention, remote ischemic conditioning can reduce the ischemicOn the basis of the common mechanisms of remote ischemic conditioning and sleep regulation, a causalrelationship was proposed between remote ischemic conditioning and post-stroke sleep quality.

Keywords： remote ischemic conditioning     sleep regulation     stroke    

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Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 108-115 doi: 10.1007/s11684-019-0730-8

Abstract: Post-transplantation cyclophosphamide (PT-Cy) alone or in combination with other immunosuppressive drugsPT-Cy combined with cyclosporine as graft-versus-host disease (GVHD) prophylaxis after myeloablative conditioning

Keywords： post-transplantation cyclophosphamide     allogeneic hematopoietic stem cell transplantation     lymphoid malignancies    

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Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 79-90 doi: 10.1007/s11684-020-0783-8

Abstract: Natural killer (NK) cells, a type of cytotoxic lymphocytes, can infiltrate into ischemic brain and exacerbateThis study investigated the effects of ASIV on post-ischemic brain infiltration and activation of NKASIV inhibited astrocyte-derived CCL2 upregulation and reduced CCR2 NK cell levels in the ischemic brainASIV restored acetylation of histone H3 and the p65 subunit of nuclear factor-κB in the ischemic brainOur findings suggest that ASIV inhibits post-ischemic NK cell brain infiltration and activation and reverses

Keywords： astragaloside IV     brain ischemia     natural killer cells     histone deacetylase     nuclear factor-κB    

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Cardiac Remote Conditioning and Clinical Relevance: All Together Now! Review

Kristin Luther,Yang Song,Yang Wang,Xiaoping Ren,W. Keith Jones

Engineering 2015, Volume 1, Issue 4,   Pages 490-499 doi: 10.15302/J-ENG-2015117

Abstract: In ischemic preconditioning (IPC) and ischemic postconditioning, ischemia within the heart initiatespre-, per-, and post-conditioning, respectively.or non-ischemic stimuli.” phenomena represent activation from different entry points of a cardiac conditioning networknon-traumatic means to initiate cardiac conditioning.

Keywords： remote cardioprotection     cardiac conditioning     non-ischemic conditioning     peripheral nociceptive stimulus    

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Genetics of ischemic and hemorrhagic stroke in Chinese population

Wei-Li ZHANG MD, PhD, Ru-Tai HUI MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 21-28 doi: 10.1007/s11684-010-0013-x

Abstract: the results from case-control association studies on genetic factors that play a role in the risk of ischemic

Keywords： genetics     ischemic stroke     hemorrhagic stroke     association study    

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Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Frontiers in Energy 2007, Volume 1, Issue 1,   Pages 85-90 doi: 10.1007/s11708-007-0008-8

Abstract: Solar liquid desiccant air-conditioner is a new air-conditioning system in which liquid desiccant canA principal solar liquid desiccant air-conditioning system under energy storage operating mode is proposed

Keywords： desiccant air-conditioning     regeneration process     air-conditioning system     energy     regeneration    

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Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 20-29 doi: 10.1007/s11684-014-0371-x

Abstract:

Ischemic stroke is a focal cerebral insult that often leads to many adverse neurological complicationsThis review article provides an update role of hUC-MSCs implantation in the treatment of ischemic stroke

Keywords： cellular therapy     transplantation     human umbilical cord     mesenchymal stem cells     ischemic stroke    

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Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation in ischemic

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 429-441 doi: 10.1007/s11684-021-0842-9

Abstract: The local microenvironment is essential to stem cell-based therapy for ischemic stroke, and spatiotemporalThis study aimed to investigate the microenvironmental changes in the subacute and chronic phases of ischemicHerein, induced pluripotent stem cells (iPSCs) and neural stem cells (NSCs) were transplanted into the ischemicdifferentially expressed proteins in the subacute and chronic phases, which are involved in various ischemicTaken together, our study indicated that iPSCs have a positive therapeutic effect in ischemic stroke

Keywords： ischemic stroke     microenvironment     induced pluripotent stem cells (iPSCs)     positron emission tomography    

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New developments in mobile air conditioning systems in China

Jiangping CHEN, Yu ZHAO, Zhaogang QI

Frontiers in Energy 2011, Volume 5, Issue 1,   Pages 53-58 doi: 10.1007/s11708-010-0137-3

Abstract: Global warming poses serious global concerns, and the mobile air conditioning (MAC) industry must be

Keywords： global warming potential     mobile air conditioning (MAC)     energy saving     new developments    

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Experimental investigation on desiccant air-conditioning system in India

Vijay MITTAL, B. Kant KHAN,

Frontiers in Energy 2010, Volume 4, Issue 2,   Pages 161-165 doi: 10.1007/s11708-009-0070-5

Abstract: investigation in India was presented to evaluate the performance and energy saving capacity of a desiccant air-conditioningAs expected, simple economic analysis indicates that the desiccant air-conditioning is not viable for

Keywords： air ratios     ambient conditions     desiccant air-conditioning     silica gel    

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Research progress in liquid desiccant air-conditioning devices and systems

Xiaohua LIU, Yi JIANG, Shuanqiang LIU, Xiaoyang CHEN,

Frontiers in Energy 2010, Volume 4, Issue 1,   Pages 55-65 doi: 10.1007/s11708-009-0082-1

Abstract: The developments on liquid desiccant air-conditioning systems were illustrated and summarized in thisThe liquid desiccant air processor-based temperature and humidity-independent control air-conditioningsystem could save 20%–30% operating energy compared with the conventional air-conditioning system

Keywords： liquid desiccant     heat and mass transfer     performance     air-conditioning    

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Engine-driven hybrid air-conditioning system

Chaokui QIN , Hongmei LU , Xiong LIU , Gerhard SCHMITZ ,

Frontiers in Energy 2009, Volume 3, Issue 1,   Pages 109-116 doi: 10.1007/s11708-009-0003-3

Abstract: A hybrid air-conditioning system that combines an engine-driven chiller with desiccant dehumidification

Keywords： engine-driven chiller     desiccant wheel     hybrid air-conditioning system     energy consumption    

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Predication of increased plasma homocysteine level on the prognosis of Chinese patients with first-onset ischemic

YAN Jiangtao, SHAO Jiaomei, WANG Daowen, YUE Zhengliang, HUI Rutai

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 352-355 doi: 10.1007/s11684-008-0067-1

Abstract: One hundred ninety six patients with first-onset ischemic stroke and ninety-five patients with first-onsetSurvival analysis shows that the probability of death or new vascular events in the ischemic stroke patientsThe relative risk of death or new vascular events was 2.363 (95% CI, 1.209 to 4.617, = 0.012) in ischemicthe risk of death or new vascular events (, 2.492, 95% CI, 1.148 to 5.407, = 0.021) in patients with ischemicIncreased tHcy level was an independent risk factor for a worse outcome in patients with first-onset ischemic
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Efficacy and safety of JAK inhibitor INC424 in patients with primary and post-polycythemia vera or post-essential

Xin Du,Daobin Zhou

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 437-443 doi: 10.1007/s11684-016-0472-9

Abstract:

A phase II study (A2202) was performed to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in 63 Chinese MF patients. Ruxolitinib was given twice a day (bid) at a starting dose of 15 mg (n=25) or 20 mg (n=38) based on a baseline platelet count. About 94.7% of the patients achieved a reduction in spleen size, 27.0% of which exhibited significant reduction (≥35%) at week 24. Significant improvement in debilitating constitutional symptoms, as assessed by MFSAF v2.0, was observed in patients treated with ruxolitinib. Ruxolitinib treatment was generally well tolerated by Chinese patients. Although the treatment was associated with an increase in certain adverse events (AEs) that were established as identified risks (anemia and thrombocytopenia), these AEs were considered manageable in this clinical setting. Ruxolitinib provided substantial reductions in splenomegaly and improvements in symptoms, and was well-tolerated by Chinese patients with MF.

Keywords： JAK     ruxolitinib     Chinese patients     myelofibrosis    

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Title Author Date Type Operation

Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemicpost-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Journal Article

Interactions between remote ischemic conditioning and post-stroke sleep regulation

Journal Article

Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Journal Article

Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

Journal Article

Cardiac Remote Conditioning and Clinical Relevance: All Together Now!

Kristin Luther,Yang Song,Yang Wang,Xiaoping Ren,W. Keith Jones

Journal Article

Genetics of ischemic and hemorrhagic stroke in Chinese population

Wei-Li ZHANG MD, PhD, Ru-Tai HUI MD, PhD,

Journal Article

Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Journal Article

Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Journal Article

Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation in ischemic

Journal Article

New developments in mobile air conditioning systems in China

Jiangping CHEN, Yu ZHAO, Zhaogang QI

Journal Article

Experimental investigation on desiccant air-conditioning system in India

Vijay MITTAL, B. Kant KHAN,

Journal Article

Research progress in liquid desiccant air-conditioning devices and systems

Xiaohua LIU, Yi JIANG, Shuanqiang LIU, Xiaoyang CHEN,

Journal Article

Engine-driven hybrid air-conditioning system

Chaokui QIN , Hongmei LU , Xiong LIU , Gerhard SCHMITZ ,

Journal Article

Predication of increased plasma homocysteine level on the prognosis of Chinese patients with first-onset ischemic

YAN Jiangtao, SHAO Jiaomei, WANG Daowen, YUE Zhengliang, HUI Rutai

Journal Article

Efficacy and safety of JAK inhibitor INC424 in patients with primary and post-polycythemia vera or post-essential

Xin Du,Daobin Zhou

Journal Article